USP6 anticorps

N° du produit ABIN6265934

Détail du produit anti-USP6 anticorps

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP6 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: USP6 Antibody detects endogenous levels of total USP6

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human USP6

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur USP6

Antigène: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Autre désignation: USP6 (USP6 Produits)

Synonymes: anticorps HRP1, anticorps TRE2, anticorps TRE17, anticorps Tre-2, anticorps USP6-short, anticorps ubiquitin specific peptidase 6, anticorps ubiquitin carboxyl-terminal hydrolase 6, anticorps Ubiquitin carboxyl-terminal hydrolase 6, putative, anticorps USP6, anticorps CNG04540, anticorps ANI_1_2152104, anticorps AOR_1_208094, anticorps MCYG_00569, anticorps CC1G_15273, anticorps MGYG_01395, anticorps CGB_G0160W, anticorps LOC100282385

Sujet:

Description: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Gene: USP6

Poids moléculaire: 159 kDa

ID gène: 9098

UniProt: P35125