ZBTB33 anticorps (N-Term)

N° du produit ABIN6266090

Cet anticorps Lapin Polyclonal détecte spécifiquement ZBTB33 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ZBTB33 anticorps (N-Term) (ABIN6266090)

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB33 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ZBTB33 anticorps

Épitope: N-Term

Specificité: ZBTB33 Antibody detects endogenous levels of total ZBTB33.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ZBTB33, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ZBTB33

Antigène: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Autre désignation: ZBTB33

Sujet:

Description: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).

Gene: ZBTB33

Poids moléculaire: 74 kDa

ID gène: 10009

UniProt: Q86T24