ZKSCAN3 anticorps (Internal Region)
Aperçu rapide pour ZKSCAN3 anticorps (Internal Region) (ABIN6266108)
Antigène
Voir toutes ZKSCAN3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- ZKSCAN3 Antibody detects endogenous levels of total ZKSCAN3.
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human ZKSCAN3, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))
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Autre désignation
- ZKSCAN3
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Sujet
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Description: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
Gene: ZKSCAN3
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Poids moléculaire
- 61 kDa
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ID gène
- 80317
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UniProt
- Q9BRR0
Antigène
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