Histone Cluster 2, H4a (HIST2H4A) (Lys20) anticorps

N° du produit ABIN6266164

Cet anticorps anti-Histone Cluster 2, H4a Polyclonal Lapin (ABIN6266164) détecte spécifiquement Histone Cluster 2, H4a dans WB, ELISA, ICC, ChIP, IF et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Histone Cluster 2, H4a (HIST2H4A) (Lys20) anticorps (ABIN6266164)

Antigène: Histone Cluster 2, H4a (HIST2H4A)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit

Épitope: Lys20

Specificité: HIST2H4A Antibody detects endogenous levels of total HIST2H4A

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200 IP 1:50-1:200 CHIP 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détail du antigène

Antigène: Histone Cluster 2, H4a (HIST2H4A)

Autre désignation: HIST2H4A

Sujet:

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4

Poids moléculaire: 11kDa

ID gène: 121, 504, 554

UniProt: P62805

Pathways: Telomere Maintenance