ABCB11 anticorps

N° du produit ABIN6291730

Cet anticorps Lapin Polyclonal détecte spécifiquement ABCB11 dans WB. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour ABCB11 anticorps (ABIN6291730)

Antigène: ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCB11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ABCB11 anticorps

Purification: Affinity purification

Immunogène: A synthetic peptide of human ABCB11

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Commentaires:

Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur ABCB11

Antigène: ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

Autre désignation: ABCB11

Sujet: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

Poids moléculaire: 146.407 kDa

ID gène: 8647

UniProt: O95342