ALX4 anticorps
Aperçu rapide pour ALX4 anticorps (ABIN6292606)
Antigène
Voir toutes ALX4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- Recombinant Protein of human ALX4
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Isotype
- IgG
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Indications d'application
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 -
Commentaires
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Expression is likely to be restricted to bone, Found in parietal bone
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20C. Avoid freeze / thaw cycles.
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- ALX4 (ALX Homeobox 4 (ALX4))
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Autre désignation
- ALX4
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Sujet
- This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.
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Poids moléculaire
- 44.241 kDa
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ID gène
- 60529
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UniProt
- Q9H161
Antigène
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