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ALX4 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement ALX4 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN6292606

Aperçu rapide pour ALX4 anticorps (ABIN6292606)

Antigène

Voir toutes ALX4 Anticorps
ALX4 (ALX Homeobox 4 (ALX4))

Reactivité

  • 34
  • 10
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 31
  • 4
Lapin

Clonalité

  • 31
  • 4
Polyclonal

Conjugué

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ALX4 est non-conjugé

Application

  • 23
  • 13
  • 9
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Purification

    Affinity purification

    Immunogène

    Recombinant Protein of human ALX4

    Isotype

    IgG
  • Indications d'application

    WB 1:500 - 1:2000
    IHC 1:50 - 1:200

    Commentaires

    Expression is likely to be restricted to bone, Found in parietal bone

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20C. Avoid freeze / thaw cycles.
  • Antigène

    ALX4 (ALX Homeobox 4 (ALX4))

    Autre désignation

    ALX4

    Sujet

    This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

    Poids moléculaire

    44.241 kDa

    ID gène

    60529

    UniProt

    Q9H161
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