Transforming Protein Myb (AA 119-135) anticorps

N° du produit ABIN6294290

L’anticorps anti-Transforming Protein Myb Monoclonal Souris est utilisé pour la détection de Transforming Protein Myb dans des échantillons de Humain. Il a été validé pour FACS et IF.

Aperçu rapide pour Transforming Protein Myb (AA 119-135) anticorps (ABIN6294290)

Antigène: Transforming Protein Myb

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit

Épitope: AA 119-135

Fonction: Mouse anti-Human c-Myb Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Immunogène: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détail du antigène

Antigène: Transforming Protein Myb

Sujet:

Target Description: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

Gene Symbol: V-MYB

UniProt: P01104