VWF anticorps (AA 1815-1939)
Aperçu rapide pour VWF anticorps (AA 1815-1939) (ABIN6294346)
Antigène
Voir toutes VWF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1815-1939
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Fonction
- Rabbit anti-Human Recombinant von Willebrand Factor / vWFAntibody [IHC only]
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Specificité
- Cytoplasmic
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Purification
- Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.
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Immunogène
- Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.
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Indications d'application
- Prediluted IHC only format: incubate for 30 min at RT (1)
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Restrictions
- For Research Use only
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Buffer
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, For IHC use only
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- VWF (Von Willebrand Factor (VWF))
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Autre désignation
- von Willebrand factor ]
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Sujet
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Target Description: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Gene Symbol: VWF///F8VWF
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ID gène
- 7450
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UniProt
- P04275
Antigène
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