EpCAM anticorps (AA 20-60)
Aperçu rapide pour EpCAM anticorps (AA 20-60) (ABIN6294377)
Antigène
Voir toutes EpCAM (EPCAM) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 20-60
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Fonction
- Rabbit anti-Human/rat Recombinant EpCAM Antibody [Sodium Azide Free]
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Specificité
- Cell surface, cytoplasmic
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Purification
- A portion of amino acids 20-60 was used as the immunogen for the recombinant EpCAM antibody.
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Immunogène
- A portion of amino acids 20-60 was used as the immunogen for the recombinant EpCAM antibody.
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Indications d'application
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Western blot: 0.5-1 μg/mL
IF: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
Prediluted IHC only format: incubate for 30 min at RT (1)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
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Autre désignation
- Epithelial cell adhesion molecule
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Sujet
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Target Description: Recognizes a 40-43 kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). EpCAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
Gene Symbol: EPCAM///GA733-2///M1S2///M4S1///MIC18///TACSTD1///TROP1
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ID gène
- 4072
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UniProt
- P16422
Antigène
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