TEAD2 anticorps (Center)

N° du produit ABIN6294438

Cet anticorps anti-TEAD2 est un anticorps Lapin Polyclonal détectant TEAD2 dans . Adapté pour Humain et Souris.

Aperçu rapide pour TEAD2 anticorps (Center) (ABIN6294438)

Antigène: TEAD2 (TEA Domain Family Member 2 (TEAD2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEAD2 est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-TEAD2 anticorps

Épitope: AA 267-295, Center

Fonction: Rabbit Anti-TEAD2 (Center) Antibody

Immunogène: This TEAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the Central region of human TEAD2.

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur TEAD2

Antigène: TEAD2 (TEA Domain Family Member 2 (TEAD2))

Autre désignation: TEAD2

Sujet:

Target Description: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

Gene Symbol: TEAD2

ID gène: 8463

UniProt: Q15562

Pathways: Regulation of Lipid Metabolism by PPARalpha, Tube Formation