GP2 anticorps (AA 35-179)

N° du produit ABIN6294488

L’anticorps anti-GP2 Monoclonal Souris est utilisé pour la détection de GP2 dans des échantillons de Humain. Il a été validé pour IHC, FACS et IF.

Aperçu rapide pour GP2 anticorps (AA 35-179) (ABIN6294488)

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GP2 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-GP2 anticorps

Épitope: AA 35-179

Fonction: Mouse anti-Human Glycoprotein 2 Antibody / GP2 / ZAP75 [Sodium Azide Free]

Specificité: Cytoplasmic, membranous, secreted

Purification: A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the GP2 antibody.

Immunogène: A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the GP2 antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/10e6 cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur GP2

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Autre désignation: Pancreatic secretory granule membrane major glycoprotein GP2

Sujet:

Target Description: GP2 (Glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

Gene Symbol: GP2

ID gène: 2813

UniProt: P55259