p63 anticorps (AA 5-17)

N° du produit ABIN6294546

Cet anticorps anti-p63 est un anticorps Lapin Polyclonal détectant p63 dans WB, IHC, IF et FACS. Adapté pour Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour p63 anticorps (AA 5-17) (ABIN6294546)

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp p63 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-p63 anticorps

Épitope: AA 5-17

Fonction: Rabbit anti-Human/Mouse/Rat/Cow p40 Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: Amino acids ENNAQTQFSEPQY (aa 5-17) of human p40 / p63 delta were used as the immunogen for this antibody.

Immunogène: Amino acids ENNAQTQFSEPQY (aa 5-17) of human p40 / p63 delta were used as the immunogen for this antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/10e6 cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur p63

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Autre désignation: Tumor protein 63

Sujet:

Target Description: p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p40 antibody 's ability to distinguish between the tumor types appears to be superior when compared to p63. The ability to utilize a p40 antibody probe as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.

Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L

ID gène: 8626

UniProt: Q9H3D4