TFF1 anticorps (C-Term)

N° du produit ABIN6294638

L’anticorps Souris Monoclonal anti-TFF1 a été validé pour IHC et IF. Il convient pour détecter TFF1 dans des échantillons de Humain.

Aperçu rapide pour TFF1 anticorps (C-Term) (ABIN6294638)

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TFF1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TFF1 anticorps

Épitope: C-Term

Fonction: Mouse anti-Human TFF1 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: A C-terminus peptide was used as the immunogen for the TFF1 antibody.

Immunogène: A C-terminus peptide was used as the immunogen for the TFF1 antibody.

Information d'application

Indications d'application: Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur TFF1

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: Trefoil factor 1

Sujet:

Target Description: TFF1/Breast cancer estrogen inducible protein pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. TFF1/pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. TFF1 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract.

Gene Symbol: TFF1///BCEI///PS2

ID gène: 7031

UniProt: P04155

Pathways: EGFR Signaling Pathway