VLDLR anticorps (C-Term)
Aperçu rapide pour VLDLR anticorps (C-Term) (ABIN6294641)
Antigène
Voir toutes VLDLR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Mouse anti-Human/Rat VLDLR Antibody [Sodium Azide Free]
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Specificité
- Cytoplasmic
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Purification
- A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.
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Immunogène
- A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.
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Indications d'application
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FACS: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
Western blot: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL (1) -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
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Autre désignation
- Very low-density lipoprotein receptor
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Sujet
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Target Description: Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
Gene Symbol: VLDLR
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ID gène
- 7436
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UniProt
- P98155
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
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