Ubiquitin Hydrolase Isozyme L1 (C-Term) anticorps
Aperçu rapide pour Ubiquitin Hydrolase Isozyme L1 (C-Term) anticorps (ABIN6294652)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Mouse anti-Human/Mouse/Rat/Cow/Pig PGP9.5 Antibody UchL1 [IHC only]
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Specificité
- Cytoplasmic
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Purification
- Native protein from brain was used as the immunogen for this PGP9.5 antibody.
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Immunogène
- Native protein from brain was used as the immunogen for this PGP9.5 antibody.
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Indications d'application
- Prediluted format : incubate for 30 min at RT (2)
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Restrictions
- For Research Use only
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Buffer
- Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Ubiquitin Hydrolase Isozyme L1
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Sujet
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Target Description: This antibody specifically reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. PGP9.5 antibody has been used to show the protein to be a useful prognostic indicator of colorectal, pancreatic and gall bladder cancer. A mutation in the gene is believed to cause a form of Parkinson's disease.
Gene Symbol: UCHL1
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ID gène
- 7345
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UniProt
- P09936
Antigène
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