SUMO2 anticorps (C-Term)
Aperçu rapide pour SUMO2 anticorps (C-Term) (ABIN6294661)
Antigène
Voir toutes SUMO2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Mouse Anti-SUMO2 (C-term) Antibody
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Immunogène
- Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody.
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
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Autre désignation
- SUMO2
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Sujet
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Target Description: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
Gene Symbol: SUMO2
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ID gène
- 6613
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UniProt
- P61956
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Pathways
- Methionine Biosynthetic Process
Antigène
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