CSE1L anticorps (C-Term)

N° du produit ABIN6295024

Cet anticorps Lapin Polyclonal détecte spécifiquement CSE1L dans . Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CSE1L anticorps (C-Term) (ABIN6295024)

Antigène: CSE1L (Chromosome Segregation 1-Like (CSE1L))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSE1L est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-CSE1L anticorps

Épitope: AA 55-84, C-Term

Fonction: Rabbit Anti-Cellular Apoptosis Susceptibility (C-term) Antibody

Immunogène: This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility.

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur CSE1L

Antigène: CSE1L (Chromosome Segregation 1-Like (CSE1L))

Autre désignation: Cellular Apoptosis Susceptibility

Sujet:

Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.

Gene Symbol: CSE1L

ID gène: 1434

UniProt: P55060