ALPL anticorps (Center)

N° du produit ABIN6295240

Cet anticorps Lapin Polyclonal détecte spécifiquement ALPL dans . Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ALPL anticorps (Center) (ABIN6295240)

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALPL est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-ALPL anticorps

Épitope: AA 217-246, Center

Fonction: Rabbit Anti-ALPL (Center) Antibody

Immunogène: This ALPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the Central region of human ALPL.

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur ALPL

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Autre désignation: ALPL

Sujet:

Target Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

Gene Symbol: ALPL

ID gène: 249

UniProt: P05186