VRK1 anticorps (Center)

N° du produit ABIN6295345

Cet anticorps Lapin Polyclonal détecte spécifiquement VRK1 dans . Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour VRK1 anticorps (Center) (ABIN6295345)

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VRK1 est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-VRK1 anticorps

Épitope: AA 366-396, Center

Fonction: Rabbit Anti-VRK1 (Center) Antibody

Immunogène: This VRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-396 amino acids from the Central region of human VRK1.

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur VRK1

Antigène: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Autre désignation: VRK1

Sujet:

Target Description: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Gene Symbol: VRK1

ID gène: 7443

UniProt: Q99986