LDL anticorps (Center)
Aperçu rapide pour LDL anticorps (Center) (ABIN6295353)
Antigène
Voir toutes LDL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 391-419, Center
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Fonction
- Rabbit Anti-LDLR (Center) Antibody
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Immunogène
- This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human LDLR.
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- LDL (Low Density Lipoprotein (LDL))
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Autre désignation
- LDL
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Sujet
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Target Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
Gene Symbol: LDLR
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ID gène
- 3949
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UniProt
- P01130
Antigène
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