TIMP2 anticorps (N-Term)

N° du produit ABIN6295483

Cet anticorps Souris Monoclonal détecte spécifiquement TIMP2 dans WB, IF et IHC (fp). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour TIMP2 anticorps (N-Term) (ABIN6295483)

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-TIMP2 anticorps

Épitope: N-Term

Fonction: Mouse anti-Human/Mouse/Rat TIMP2 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic, cell surface, secreted

Purification: An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

Immunogène: An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

Information d'application

Indications d'application: IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
WB: 0.5-1 μg/mL
IF: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur TIMP2

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Autre désignation: Metalloproteinase inhibitor 2

Sujet:

Target Description: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Gene Symbol: TIMP2

ID gène: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process