Tyrosinase-Related Protein 1 anticorps

N° du produit ABIN6295921

Cet anticorps Souris Monoclonal détecte spécifiquement Tyrosinase-Related Protein 1 dans IHC, IF et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (ABIN6295921)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps

Fonction: Mouse anti-Human/Mouse TRP1 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

Immunogène: Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: 5,6-dihydroxyindole-2-carboxylic acid oxidase

Sujet:

Target Description: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Gene Symbol: TYRP1///CAS2///TYRP///TYRRP

ID gène: 7306

UniProt: P17643