Keratin 10 anticorps

N° du produit ABIN6295936

Cet anticorps Souris Monoclonal détecte spécifiquement Keratin 10 dans IHC, FACS et IF. Il présente une réactivité envers Humain, Chien et Cat.

Aperçu rapide pour Keratin 10 anticorps (ABIN6295936)

Antigène: Keratin 10 (KRT10)

Reactivité: Humain, Chien, Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 10 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-Keratin 10 anticorps

Fonction: Mouse anti-Human/Dog/Cat Cytokeratin 10 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: A cytoskeletal preparation extracted from human ectocervical epithelium was used as the immunogen for the Cytokeratin 10 antibody.

Immunogène: A cytoskeletal preparation extracted from human ectocervical epithelium was used as the immunogen for the Cytokeratin 10 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Keratin 10

Antigène: Keratin 10 (KRT10)

Autre désignation: Keratin, type I cytoskeletal 10

Sujet:

Target Description: This mAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Gene Symbol: KRT10///KPP

ID gène: 3858

UniProt: P13645