PD-1 anticorps
Aperçu rapide pour PD-1 anticorps (ABIN6295971)
Antigène
Voir toutes PD-1 (PDCD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit anti-Human PDCD1 / PD-1 Antibody [Sodium Azide Free]
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Specificité
- Cell surface & cytoplasmic
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Purification
- A full-length human protein was used as the immunogen for the PD1 antibody.
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Immunogène
- A full-length human protein was used as the immunogen for the PD1 antibody.
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Indications d'application
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Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
Immunofluorescence: 1-2 μg/mL
FACS: 0.5-1 μg/10e6 cells in 0.1ml -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Autre désignation
- Programmed cell death protein 1
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Sujet
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Target Description: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
Gene Symbol: PDCD1///PD1
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ID gène
- 5133
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UniProt
- Q15116
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Pathways
- Cancer Immune Checkpoints
Antigène
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