Nkx2-2 anticorps

N° du produit ABIN6296003

L’anticorps Lapin Polyclonal anti-Nkx2-2 a été validé pour IF, IHC et FACS. Il convient pour détecter Nkx2-2 dans des échantillons de Humain.

Aperçu rapide pour Nkx2-2 anticorps (ABIN6296003)

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nkx2-2 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-Nkx2-2 anticorps

Fonction: Rabbit anti-Human NKX2.2 Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

Immunogène: A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/10e6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Nkx2-2

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Autre désignation: Homeobox protein Nkx-2.2

Sujet:

Target Description: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

Gene Symbol: NKX2-2///NKX2.2///NKX2B

ID gène: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis