RNMT anticorps

N° du produit ABIN6296037

Cet anticorps anti-RNMT est un anticorps Souris Monoclonal détectant RNMT dans IHC, IF et FACS. Adapté pour Humain, Rat, Boeuf (Vache), Chien et Hamster.

Aperçu rapide pour RNMT anticorps (ABIN6296037)

Antigène: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNMT est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-RNMT anticorps

Fonction: Mouse anti-Human/Cow/Dog/Hamster/Rat TAG-72 Antibody [Sodium Azide Free]

Specificité: Cytoplasmic and cell surface

Purification: A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.

Immunogène: A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur RNMT

Antigène: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Autre désignation: mRNA cap guanine-N7 methyltransferase  

Sujet:

Target Description: Recognizes an oncofetal antigen of 220 kDa, identified as a Tumor-associated glycoprotein (TAG-72) with properties of a mucin. This mAb defines the mucin-carried sialylated-Tn epitope. TAG72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Gene Symbol: tag-72  C25A1.3

ID gène: 182875

UniProt: Q9XVS1