CD5 anticorps

N° du produit ABIN6296063

L’anticorps anti-CD5 Monoclonal Souris est utilisé pour la détection de CD5 dans des échantillons de Humain, Rat, Boeuf (Vache), Lapin, Cheval, Porc, Singe, Poulet et Cobaye. Il a été validé pour FACS, WB, IHC et IF.

Aperçu rapide pour CD5 anticorps (ABIN6296063)

Antigène: CD5

Reactivité: Humain, Rat, Boeuf (Vache), Lapin, Cheval, Porc, Singe, Poulet, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD5 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CD5 anticorps

Fonction: Mouse anti-Human/Monkey/Horse/Pig/Rabbit/Cow/Rat/Guinea Pig/Chicken CD5 Antibody [Sodium Azide Free]

Specificité: Cell surface

Purification: A peptide from the intracellular region of the human protein was used as the immunogen for this CD5 antibody.

Immunogène: A peptide from the intracellular region of the human protein was used as the immunogen for this CD5 antibody.

Information d'application

Indications d'application: Western blot: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD5

Antigène: CD5

Autre désignation: T-cell surface glycoprotein CD5

Sujet:

Target Description: Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

Gene Symbol: CD5///LEU1

ID gène: 921

UniProt: P06127