Desmoglein 1 anticorps

N° du produit ABIN6296099

L’anticorps Souris Monoclonal anti-Desmoglein 1 a été validé pour WB, IF, FACS et IP. Il convient pour détecter Desmoglein 1 dans des échantillons de Humain.

Aperçu rapide pour Desmoglein 1 anticorps (ABIN6296099)

Antigène: Desmoglein 1 (DSG1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Détail du produit anti-Desmoglein 1 anticorps

Fonction: Mouse anti-Human Desmoglein 1 Antibody / DSG1 [Sodium Azide Free]

Specificité: Cell surface

Purification: A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.

Immunogène: A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.

Information d'application

Indications d'application: FACS: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunoprecipitation: suitable

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Desmoglein 1

Antigène: Desmoglein 1 (DSG1)

Autre désignation: Desmoglein-1

Sujet:

Target Description: Desmoglein 1 (DSG1) is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.

Gene Symbol: DSG1///CDHF4

ID gène: 1828

UniProt: Q02413

Pathways: Cell-Cell Junction Organization