WT1 anticorps
Aperçu rapide pour WT1 anticorps (ABIN6296102)
Antigène
Voir toutes WT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit anti-Human Recombinant WT1 Antibody / Wilms Tumor 1 [Sodium Azide Free]
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Specificité
- Cytoplasmic, membranous
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Purification
- A recombinant protein was used as the immunogen for the recombinant WT1 antibody.
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Immunogène
- A recombinant protein was used as the immunogen for the recombinant WT1 antibody.
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Indications d'application
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FACS: 0.5-1 μg/10e6 cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT
Prediluted IHC only format: incubate for 30 min at RT (1) -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- WT1 (Wilms Tumor 1 (WT1))
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Autre désignation
- Wilms tumor protein
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Sujet
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Target Description: Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Gene Symbol: WT1
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ID gène
- 7490
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UniProt
- P19544
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Pathways
- Tube Formation
Antigène
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