CNN1 anticorps

N° du produit ABIN6296236

Cet anticorps Souris Monoclonal détecte spécifiquement CNN1 dans FACS, IF et IHC. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour CNN1 anticorps (ABIN6296236)

Antigène: CNN1 (Calponin 1 (CNN1))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CNN1 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-CNN1 anticorps

Fonction: Mouse anti-Human/Rat Calponin Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: Crude human uterus extract was used as the immunogen for the Calponin antibody.

Immunogène: Crude human uterus extract was used as the immunogen for the Calponin antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CNN1

Antigène: CNN1 (Calponin 1 (CNN1))

Autre désignation: Calponin-1

Sujet:

Target Description: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this mAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

Gene Symbol: CNN1

ID gène: 1264

UniProt: P51911