NEFL anticorps
Aperçu rapide pour NEFL anticorps (ABIN6296239)
Antigène
Voir toutes NEFL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human/Rat/Pig/Cow/Chicken Neurofilament Antibody [Sodium Azide Free]
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Specificité
- Cytoplasmic
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Purification
- Crude neurofilament preparation from porcine spinal cord was used as the immunogen for the Neurofilament antibody.
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Immunogène
- Crude neurofilament preparation from porcine spinal cord was used as the immunogen for the Neurofilament antibody.
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Indications d'application
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Immunofluorescence: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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Autre désignation
- Neurofilament light polypeptide
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Sujet
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Target Description: This mAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.
Gene Symbol: NEFL///NF68///NFL
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ID gène
- 4747
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UniProt
- P07196
Antigène
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