Tropomyosin anticorps

N° du produit ABIN629646

Cet anticorps anti-Tropomyosin est un anticorps Lapin Polyclonal détectant Tropomyosin dans WB et IHC. Adapté pour Humain, Rat, Souris, Poisson zèbre (Danio rerio) et Chien.

Aperçu rapide pour Tropomyosin anticorps (ABIN629646)

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tropomyosin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Tropomyosin anticorps

Purification: Purified

Immunogène: Tropomyosin 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE

Information d'application

Indications d'application: WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Tropomyosin 1 Blocking Peptide, (ABIN937523), is also available for use as a blocking control in assays to test for specificity of this Tropomyosin 1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TPM1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur Tropomyosin

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Autre désignation: Tropomyosin 1

Sujet: TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.

Poids moléculaire: 31 kDa (MW of target protein)

Pathways: Regulation of Actin Filament Polymerization