Myeloid Cell Marker anticorps

N° du produit ABIN6296504

L’anticorps anti-Myeloid Cell Marker Monoclonal Souris est utilisé pour la détection de Myeloid Cell Marker dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Myeloid Cell Marker anticorps (ABIN6296504)

Antigène: Myeloid Cell Marker

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC)

Détail du produit

Fonction: Mouse anti-Human Myeloid Cell Marker Antibody [IHC only]

Specificité: Cytoplasmic and nuclear

Purification: Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.

Immunogène: Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détail du antigène

Antigène: Myeloid Cell Marker

Sujet:

Target Description: This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid cell specific antigen. Clone BM-1 antibody reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. This type of marker is useful in the identification of different levels of cellular differentiation. BM-1 and BM-2 antibodies react with early precursor and mature forms of human myeloid cells. This mAb is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of the marker protein is not clear, although it has been proposed that it may play a role in cell differentiation.