Histone H1 anticorps

N° du produit ABIN6296764

Cet anticorps Souris Monoclonal détecte spécifiquement Histone H1 dans WB, IHC, IF et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Histone H1 anticorps (ABIN6296764)

Antigène: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-Histone H1 anticorps

Fonction: Mouse anti-Human/Mouse/Rat Histone Antibody [Sodium Azide Free]

Specificité: Nuclear

Purification: Nuclei of human leukemia biopsy cells were used as the immunogen for the Histone antibody.

Immunogène: Nuclei of human leukemia biopsy cells were used as the immunogen for the Histone antibody.

Information d'application

Indications d'application: Western blot: 0.5-1 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Histone H1

Antigène: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Autre désignation: Histone H1.0

Sujet:

Target Description: Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer, formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80 % of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

Gene Symbol: H1F0///H1FV

ID gène: 3005

UniProt: P07305