UACA anticorps

N° du produit ABIN6296769

Cet anticorps anti-UACA est un anticorps Souris Monoclonal détectant UACA dans WB, IF et FACS. Adapté pour Humain et Souris.

Aperçu rapide pour UACA anticorps (ABIN6296769)

Antigène: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp UACA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-UACA anticorps

Fonction: Mouse anti-Human/Mouse UACA Antibody [Sodium Azide Free]

Specificité: Nuclear membrane

Purification: Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.

Immunogène: Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur UACA

Antigène: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Autre désignation: Uveal autoantigen with coiled-coil domains and ankyrin repeats

Sujet:

Target Description: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Gene Symbol: UACA///KIAA1561

ID gène: 55075

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity