Histone H1 anticorps

N° du produit ABIN6297055

Cet anticorps Souris Monoclonal détecte spécifiquement Histone H1 dans IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Histone H1 anticorps (ABIN6297055)

Antigène: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Histone H1 anticorps

Fonction: Mouse anti-Human/Mouse/Rat Histone H1 Antibody [IHC only]

Specificité: Nuclear

Purification: Recombinant full-length human protein was used as the immunogen for the Histone H1 antibody.

Immunogène: Recombinant full-length human protein was used as the immunogen for the Histone H1 antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Histone H1

Antigène: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Autre désignation: Histone H1.0

Sujet:

Target Description: Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer, formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80 % of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

Gene Symbol: H1F0///H1FV

ID gène: 3005

UniProt: P07305