Transgelin anticorps

N° du produit ABIN6297094

Cet anticorps Souris Monoclonal détecte spécifiquement Transgelin dans IHC, FACS et IF. Il présente une réactivité envers Humain, Souris, Lapin, Boeuf (Vache) et Porc.

Aperçu rapide pour Transgelin anticorps (ABIN6297094)

Antigène: Transgelin (TAGLN)

Reactivité: Humain, Souris, Lapin, Boeuf (Vache), Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transgelin est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-Transgelin anticorps

Fonction: Mouse anti-Human/Cow/Pig/Rabbit/Mouse SM22 alpha Antibody [Sodium Azide Free]

Specificité: Cytoplasmic

Purification: Recombinant full-length human protein was used as the immunogen for the SM22 antibody.

Immunogène: Recombinant full-length human protein was used as the immunogen for the SM22 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Transgelin

Antigène: Transgelin (TAGLN)

Autre désignation: Transgelin

Sujet:

Target Description: This mAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.

Gene Symbol: TAGLN///SM22///WS3-10

ID gène: 6876

UniProt: Q01995