P24 Capsid Protein anticorps

N° du produit ABIN6297130

Cet anticorps Souris Monoclonal détecte spécifiquement P24 Capsid Protein dans Coat, ELISA, ICC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour P24 Capsid Protein anticorps (ABIN6297130)

Antigène: P24 Capsid Protein

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Application: Coating (Coat), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit

Fonction: Mouse anti-Human HIV Type-1 p24 Antibody [Sodium Azide Free]

Specificité: Membrane

Purification: Recombinant HIV-1 Gag p24 protein was used as the immunogen for this antibody.

Immunogène: Recombinant HIV-1 Gag p24 protein was used as the immunogen for this antibody.

Information d'application

Indications d'application: ELISA: order BSA-free format for coating
Immunocytochemistry (Acetone or paraformaldehyde fixed): 0.5-1 μg/mL for 30 min
IF: 0.5-1 μg/mL,

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détail du antigène

Antigène: P24 Capsid Protein

Autre désignation: Capsid protein p24 ]

Classe de substances: Viral Protein

Sujet:

Target Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Gene Symbol: gag-pol

ID gène: 155348

UniProt: P04585