p63 anticorps

N° du produit ABIN6297602

L’anticorps Lapin Polyclonal anti-p63 a été validé pour IHC, IF et FACS. Il convient pour détecter p63 dans des échantillons de Humain.

Aperçu rapide pour p63 anticorps (ABIN6297602)

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp p63 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-p63 anticorps

Fonction: Rabbit anti-Human p63 Antibody / Tumor protein 63 [Sodium Azide Free]

Specificité: Nuclear

Purification: Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.

Immunogène: Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur p63

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Autre désignation: Tumor protein 63

Sujet:

Target Description: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L

ID gène: 8626

UniProt: Q9H3D4