p63 anticorps

N° du produit ABIN6297602

Détail du produit anti-p63 anticorps

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp p63 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Fonction: Rabbit anti-Human p63 Antibody / Tumor protein 63 [Sodium Azide Free]

Specificité: Nuclear

Purification: Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.

Immunogène: Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur p63

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Autre désignation: Tumor protein 63 (TP63 Produits)

Synonymes: anticorps AIS, anticorps B(p51A), anticorps B(p51B), anticorps EEC3, anticorps KET, anticorps LMS, anticorps NBP, anticorps OFC8, anticorps RHS, anticorps SHFM4, anticorps TP53CP, anticorps TP53L, anticorps TP73L, anticorps p40, anticorps p51, anticorps p53CP, anticorps p63, anticorps p73H, anticorps p73L, anticorps TP63, anticorps tp63, anticorps DNp63, anticorps id:ibd3516, anticorps tp73l, anticorps wu:fc89f04, anticorps wu:fk85h07, anticorps wu:fk88b02, anticorps Ket, anticorps P73l, anticorps Tp73l, anticorps Trp63, anticorps TRP63, anticorps AI462811, anticorps P51/P63, anticorps P63, anticorps Tp63, anticorps Trp53rp1, anticorps Xp63, anticorps ket, anticorps np63, anticorps tp73l-A, anticorps trp63, anticorps tumor protein p63, anticorps transformation related protein 63, anticorps tumor protein p63 L homeolog, anticorps TP63, anticorps tp63, anticorps Tp63, anticorps Trp63, anticorps tp63.L

Sujet:

Target Description: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L

ID gène: 8626

UniProt: Q9H3D4