Keratin 10 anticorps

N° du produit ABIN6297652

Cet anticorps Souris Monoclonal détecte spécifiquement Keratin 10 dans IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Lapin, Singe, Boeuf (Vache), Poulet et Tortue.

Aperçu rapide pour Keratin 10 anticorps (ABIN6297652)

Antigène: Keratin 10 (KRT10)

Reactivité: Humain, Souris, Rat, Chien, Lapin, Singe, Boeuf (Vache), Poulet, Tortue

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 10 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Keratin 10 anticorps

Fonction: Mouse anti-Human/Monkey/Cow/Dog/Rabbit/Mouse/Rat/Chicken/Turtle Acidic Cytokeratin Antibody [IHC only]

Specificité: Cytoplasmic

Purification: Solubilized keratin extract from human stratum corneum

Immunogène: Solubilized keratin extract from human stratum corneum

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur Keratin 10

Antigène: Keratin 10 (KRT10)

Autre désignation: Keratin, type I cytoskeletal 10

Sujet:

Target Description: Cytokeratins, also called keratins or simply CKs, are a family of fibrous structural proteins and a major structural component in the outer layer of human skin, as well as hair and nails.  There are 20 human epithelial keratins which can be divided into two subfamiles: acidic and basic (more recent human genone sequencing has identified an additional 20 members). The formation of cytokeratin intermediate filaments requires the pairing of at least one acidic and one basic subfamily member. Members of the same keratin subfamily share extended sequence homology while members of different subfamilies show only limited sequence homology.This antibody is specific for the 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), and 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Many studies have shown the usefulness of CKs as markers in cancer research and tumor diagnosis, as epithelial tumors generally maintain the same CK expression patterns as their counterpart normal tissue. Clone AE1 is commonly used with clone AE3 as a pan cytokeratin antibody cocktail (< a href=../pan-cytokeratin-antibody-cocktail-ae1-ae3-v2330>Cat No V2330).

Gene Symbol: KRT10///KPP

ID gène: 3858

UniProt: P13645