ICAM-3/CD50 anticorps

N° du produit ABIN6297675

Cet anticorps anti-ICAM-3/CD50 est un anticorps Souris Monoclonal détectant ICAM-3/CD50 dans FACS, IF, IHC et Func. Adapté pour Humain.

Aperçu rapide pour ICAM-3/CD50 anticorps (ABIN6297675)

Antigène: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ICAM-3/CD50 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Functional Studies (Func)

Détail du produit anti-ICAM-3/CD50 anticorps

Fonction: Mouse anti-Human ICAM-3 Antibody [Sodium Azide Free]

Specificité: Cell surface

Purification: Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.

Immunogène: Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.

Information d'application

Indications d'application: Functional Activity: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur ICAM-3/CD50

Antigène: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Autre désignation: Intercellular adhesion molecule 3

Sujet:

Target Description: Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb is excellent for staining of formalin/paraffin tissues.

Gene Symbol: ICAM3

ID gène: 3385

UniProt: P32942