CD46 anticorps

N° du produit ABIN6297689

L’anticorps Souris Monoclonal anti-CD46 a été validé pour FACS et IF. Il convient pour détecter CD46 dans des échantillons de Humain et Babouin.

Aperçu rapide pour CD46 anticorps (ABIN6297689)

Antigène: CD46

Reactivité: Humain, Babouin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-CD46 anticorps

Fonction: Mouse anti-Human/Baboon CD46 Antibody [Sodium Azide Free]

Specificité: Cell surface

Purification: Stimulated human leukocytes were used as the immunogen for the CD46 antibody.

Immunogène: Stimulated human leukocytes were used as the immunogen for the CD46 antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD46

Antigène: CD46

Autre désignation: Membrane cofactor protein

Sujet:

Target Description: Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

Gene Symbol: CD46///MCP///MIC10

ID gène: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization