CD53 anticorps

N° du produit ABIN6297690

Cet anticorps anti-CD53 est un anticorps Souris Monoclonal détectant CD53 dans FACS, IF et Func. Adapté pour Humain.

Aperçu rapide pour CD53 anticorps (ABIN6297690)

Antigène: CD53

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD53 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Détail du produit anti-CD53 anticorps

Fonction: Mouse anti-Human CD53 Antibody [Sodium Azide Free]

Specificité: Cell surface

Purification: Stimulated human leukocytes were used as the immunogen for the CD53 antibody.

Immunogène: Stimulated human leukocytes were used as the immunogen for the CD53 antibody.

Information d'application

Indications d'application: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CD53

Antigène: CD53

Autre désignation: Leukocyte surface antigen CD53

Sujet:

Target Description: Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI, Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This mAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).

Gene Symbol: CD53///MOX44///TSPAN25

ID gène: 963

UniProt: P19397