ICAM-3/CD50 anticorps
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- Antigène Voir toutes ICAM-3/CD50 (ICAM3) Anticorps
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ICAM-3/CD50 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Fonction
- Mouse anti-Human ICAM-3 Antibody [Sodium Azide Free]
- Specificité
- Cell surface
- Purification
- Stimulated human leukocytes were used as the immunogen for the ICAM-3 antibody.
- Immunogène
- Stimulated human leukocytes were used as the immunogen for the ICAM-3 antibody.
- Top Product
- Discover our top product ICAM3 Anticorps primaire
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- Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1) - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Antigène
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
- Autre désignation
- Intercellular adhesion molecule 3 (ICAM3 Produits)
- Synonymes
- anticorps CD50, anticorps CDW50, anticorps ICAM-R, anticorps ICAM-3, anticorps ICAM3, anticorps intercellular adhesion molecule 3, anticorps ICAM3, anticorps Icam3
- Sujet
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Target Description: Recognizes an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (WS: IV & V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC, cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This mAb is excellent for staining of formalin/paraffin tissues.
Gene Symbol: ICAM3
- ID gène
- 3385
- UniProt
- P32942
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