IGKV1D-16 anticorps

N° du produit ABIN6297706

Détail du produit anti-IGKV1D-16 anticorps

Antigène: IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGKV1D-16 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB)

Fonction: Mouse anti-Human Kappa Light Chain Antibody [Sodium Azide Free]

Specificité: Cell surface, cytoplasmic and secreted

Purification: Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.

Immunogène: Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.

Information d'application

Indications d'application: Flow Cytometry: 0.5-2.0 μg/million cells in 0.1ml
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur IGKV1D-16

Antigène: IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))

Autre désignation: Immunoglobulin kappa variable 1D-16 (IGKV1D-16 Produits)

Synonymes: anticorps IGKV1D16, anticorps L15, anticorps L15a, anticorps immunoglobulin kappa variable 1D-16, anticorps IGKV1D-16

Sujet:

Target Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Gene Symbol: IGKV1D-16///IGKC

ID gène: 3514

UniProt: P01601, P01834