GLG1 anticorps

N° du produit ABIN6297736

Cet anticorps Souris Monoclonal détecte spécifiquement GLG1 dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour GLG1 anticorps (ABIN6297736)

Antigène: GLG1 (Golgi Glycoprotein 1 (GLG1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GLG1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-GLG1 anticorps

Fonction: Mouse anti-Human Golgi Marker Antibody [IHC only]

Specificité: Golgi complex in cytoplasm

Purification: The Golgi fraction from human liver cells was used as the immunogen for the Golgi Marker antibody.

Immunogène: The Golgi fraction from human liver cells was used as the immunogen for the Golgi Marker antibody.

Information d'application

Indications d'application: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur GLG1

Antigène: GLG1 (Golgi Glycoprotein 1 (GLG1))

Autre désignation: Golgi apparatus protein 1

Sujet:

Target Description: This mAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This mAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This mAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

Gene Symbol: GLG1///CFR1///ESL1///MG160

ID gène: 2734

UniProt: Q92896