CD20 anticorps (PE)

N° du produit ABIN6297750

Cet anticorps anti-CD20 est un anticorps Souris Monoclonal détectant CD20 dans FACS, IF et T. Adapté pour Humain.

Aperçu rapide pour CD20 anticorps (PE) (ABIN6297750)

Antigène: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD20 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Détail du produit anti-CD20 anticorps (PE)

Fonction: Mouse anti-Human CD20 Antibody [PE Conjugated]

Specificité: Predominantly cell surface with some cytoplasmic

Purification: The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.

Immunogène: The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.

Information d'application

Indications d'application: Flow Cytometry: 5 µL per test per one million cells in 0.1 mL (or 5 µL per 100 µL of whole blood)
Immunofluorescence: 1:50-1:100

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C. The conjugate is light-sensitive, protect from light.

Détails sur CD20

Antigène: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Autre désignation: B-lymphocyte antigen CD20

Sujet:

Target Description: This antibody recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V, Code CD20.12). The antibody recognizes the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.

Gene Symbol: MS4A1///CD20

ID gène: 931

UniProt: P11836