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IGHM anticorps

IGHM Reactivité: Humain IHC, FACS, IF Hôte: Souris Monoclonal unconjugated
N° du produit ABIN6297768
  • Antigène Tous les produits IGHM
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    Reactivité
    • 26
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 14
    • 13
    Souris
    Clonalité
    • 17
    • 10
    Monoclonal
    Conjugué
    • 23
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGHM est non-conjugé
    Application
    • 13
    • 13
    • 12
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Fonction
    Mouse anti-Human IgM Antibody [Sodium Azide Free]
    Specificité
    Cytoplasm, cell surface and secreted
    Purification
    The Mu heavy chain of human Ig was used as the immunogen for the Anti-IgM antibody.
    Immunogène
    The Mu heavy chain of human Ig was used as the immunogen for the Anti-IgM antibody.
  • Indications d'application
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    Restrictions
    For Research Use only
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Agent conservateur
    Azide free
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Antigène
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    Autre désignation
    Immunoglobulin heavy constant mu (IGHM Produits)
    Synonymes
    anticorps AI326478, anticorps Igh-6, anticorps Igh-M, anticorps Igh6, anticorps Igm, anticorps muH, anticorps ighm1, anticorps wu:fj14a08, anticorps zgc:101769, anticorps AGM1, anticorps MU, anticorps VH, anticorps immunoglobulin heavy constant mu, anticorps Ighm, anticorps ighm, anticorps IGHM
    Sujet

    Target Description: Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

    Gene Symbol: IGHM

    ID gène
    3507
    UniProt
    P01871
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