PGC anticorps (Biotin)

N° du produit ABIN6297820

Détail du produit anti-PGC anticorps (Biotin)

Antigène: PGC (Pepsinogen C (PGC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PGC est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Fonction: Mouse anti-Human PGC Biotinylated Antibody

Immunogène: This antibody was produced by fusion of mouse myeloma with B cells obtained from a mouse immunized with a recombinant protein immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

Clone: 4A3-G4-G6

Isotype: IgG1

Information d'application

Indications d'application: ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)

Restrictions: For Research Use only

Stockage

Reconstitution: A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: -20°C

Détails sur PGC

Antigène: PGC (Pepsinogen C (PGC))

Autre désignation: PGC (PGC Produits)

Synonymes: anticorps PEPC, anticorps PGII, anticorps 2210410L06Rik, anticorps Upg-1, anticorps Upg1, anticorps CPGC, anticorps gastricsin, anticorps PG1, anticorps Pg-1, anticorps PGNC, anticorps PGC, anticorps Gastricsin, anticorps progastricsin (pepsinogen C), anticorps progastricsin, anticorps PGC, anticorps Pgc

Sujet:

Target Description: PGC gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

UniProt: P20142